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eLife 5 , e10575 (2016)

CYP1A2 is responsible for the process of demethylating caffeine, resulting in the production of the main metabolites [62] paraxanthine (1,7-dimethylxanthine, around 84%), theobromine (3,7-dimethylxanthine, 12%), and theophylline (1,3-dimethylxanthine, 4%)

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