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Recent multi-omics studies have revealed that patients with CFS/ME, especially in early disease stages, display pronounced disruptions in both gut microbial composition and metabolic profiles (Wang J.-H

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[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Birben E., Sahiner U.M., Sackesen C., Erzurum S., Kalayci O

PASC could encompass several adverse clinical impairments that may trigger chronic metabolic dysfunctions involving cardiovascular (CV), central/peripheral nervous (CNS/PNS), gastrointestinal (GI), pulmonary, reproductive, skeleto-muscular, and endocrinal systems 6,7