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Moreover, the ability of polyphenols to penetrate the BBB is compound specific and often suboptimal, necessitating advanced delivery strategies such as nanoformulations or prodrugs to enhance CNS targeting (Ramakrishna et al

Nature 562 , 600604 (2018)

Published Literature Interpretation for Research Buyers Research buyers should read literature by evidence type

[DOI] [PubMed] [Google Scholar] Goda T, Sharp B, and Wijnen H (2014)

Most investigators have observed that IL-1 increases significantly (up to 40- to 60-fold) in the brain within 24 h after stroke onset (Lambertsen et al., 2012), although there are some conflicting views (Reiter et al., 2001)

Similar content being viewed by others Introduction Intravenous anesthetics such as Dex, propofol, and ketamine have demonstrated neuroprotective effects in various neurological injury models