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Defects in formation of FANCD2 nuclear foci after cisplatin treatment can be used to indicate cisplatin sensitivity [17] and concomitant overexpression of PARP1 , FANCD2 , and TP53 predicted increasing resistance to platinum [18]

Furthermore, the effect of NQO1 on P53 has been evaluated in in both endothelial cells and various cancer cell types, such as human colon carcinoma cell

10.3164/jcbn.09-71 [DOI] [PMC free article] [PubMed] [Google Scholar] Y J., Kamath J

To validate the occurrence of ferroptosis in the mouse model, proteins from renal proximal tubular tissues were analyzed using Western blot

Spine 19 (2), 243247

In comparative studies, GHK-Cu demonstrates stronger collagen-stimulating activity and broader gene modulation scope than AHK-Cu, likely due to differences in copper binding affinity and cellular uptake kinetics