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Specifically, the activity of the SLC7A11, SLC3A2, and GYS1 genes increases, whereas the activity of the OXSM, NUBPL, NDUFA11, NCKAP1, and LRPPRC genes decreases (Zhu et al., 2023) (Table 1)

PA: Investigation, Writing - review & editing

doi: 10.3748/wjg.v12.i42.6812

4-HNE is a major end product of lipid peroxidation that is present in normal human plasma at concentrations ranging from 0.1M to 1.4M and this can increase more than 10 folds during oxidative stress in vivo [84]

22 UrsiniFMaiorinoMValenteMFerriLGregolinC

npj Aging 9 , 28 (2023)