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When copper attacks the brain, the early neurological signs may include changes in handwriting, drooling, tremors, and difficulty walking, talking, and swallowing
Jak et al., 2020)
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Reducing brain-generated acetaldehyde by silencing catalase or increasing ALDH2 activity in the VTA decreases alcohol-induced-reinforcing effects and reduces voluntary ethanol intake (141)
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Bier Block) suggest a three-compartment open model
