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Atlantic Neuroscience Institute and the Neurology Institute of New Jersey

Excitotoxicity requires the excessive activation of Glu receptors on postsynaptic neurons

4, Supplementary Table 17, Supplementary Fig

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Extracellular lactate accumulation favors migration and metastasis and acts as a reservoir of energy for non-hypoxic and OXOPHOS cells ( From the above, it is clear that metabolic symbiosis between the three zones is necessary for holistic growth and proliferation of cancer cells, and lactate shunt is the key to this metabolic adaptation. Compared to energy production, tumor growth and proliferation regulation under graded oxygen tension are much more complex

All MS/MS data were analyzed using Mascot (Matrix Science, London, UK