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In some embodiments, the otic formulation or composition comprises about 40% by weight of the carbomer

All raw reporter ion intensity values were exported to tab delimited text files for further processing and bioinformatic analysis

Increases in proinflammatory cytokine such as TNF, IL-4, IL-6 and IL-13 have all been shown to increase epithelial permeability and have been tied to increased expression of claudin-2 in animal and human models as well as decreased expression of JAM-A and occludin [152, 153]

Oncogene 27 , 70947105 (2008)

Any diluent selection, preparation, temperature, aliquoting, or post-reconstitution hold conditions must be established by a qualified laboratory under a validated SOP
