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According to the analysis of Etienne Simon-Loriere and Olivier Schwartz, compared with Alpha/Beta/Gamma/Delta, Omicron variants (BA.1/BA.2/BA.3) exhibit limited cross-neutralization and a greater phylogenetic distance

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It is clear that HIF-1 regulation pathway is a highly complex network involving several signaling cascades and overlapping mechanisms, each of which could serve as a promising target or step to intervene selectively

Finally, in the last few years some trials have been carried out specifically in non-cystic fibrosis bronchiectasis which aim to assess the efficacy of some of the treatments which are commonly used but sometimes without clear indication