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pylori- infected mice, the loss of CLDN 18 expression was found to occur first in gastric glands, while subsequently being found in the gastric neck and in the surface epithelial cells

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Although the BB-50 brush-border antigen was also localized in peritubular capillaries (Mutti et al., 1985), subsequent work lead to the identification of a monoclonal antibody reacting with an antigen located specifically in the brush border and thus called BBA or brush-border antigen (Mutti et al., 1988)