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Glutamine is absorbed in the upper part of the small intestine and subsequently metabolised in the liver, thus it may not be available in sufficient quantity for other tissue targets, such as immune and muscle cells, to have a measurable effect

This is also the same for L-glutathione, which is the same compound

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Biochim Biophys Acta 925:203209 Kang MJ, Gil SJ, Koh HC (2009) Paraquat induces alternation of the dopamine catabolic pathways and glutathione levels in the substantia nigra of mice

Homocysteine, B vitamins, and cardiovascular disease: A Mendelian randomization study

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