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Sci Signal (2014) 7:ra56

Xenograft experiments Four-week-old female BALB/c nude mice were purchased from Beijing Vital River Laboratory Animal Technology Co., Ltd (Beijing, China)

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This suggests tissue-specificity in -KG metabolism and provides a rationale for targeting this pathway (e.g., developing -KGDH inhibitors or -KG prodrugs) for tumor intervention (Zhang B

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The most-promoted heavy metal detox products are popular precisely because they sound natural and gentle but as chelators in humans, the evidence for them is weak to absent , and they should not be relied on to treat documented toxicity