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P53 plays a crucial role in endothelial dysfunction associated with hyperglycemia and ischemia
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Additionally, postmortem and in vitro studies that showed higher expression of active caspase-3 in the SNPC have validated apoptotic significance in the etiology of PD [341,342,343]
Further arguments might be controlling vasomotor tone and the activation of the Src-Caveolin-1-eNOS pathway [53,54]
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J Mater Chem 21:43844392
