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Vitamin D receptors and the enzymes responsible for activating vitamin D are expressed in both innate and adaptive immune cells, including monocytes, macrophages, dendritic cells, and lymphocytes

Bystander activation can trigger autoreactive T cells that may target self-antigens, including those present in the thyroid gland

Notably, pre-treatment with NAC inhibited dopamine-induced cell death, restored GSH levels, decreased HO-1 expression, and suppressed the activation of caspase-3 and caspase-9

High-risk neuroblastoma is now treated via surgical resection, myeloablative chemotherapy with hematopoietic stem cell transplantation, then adjuvant retinoid differentiation treatment and immunotherapy with anti-disialoganglioside-2 monoclonal antibodies

~ AlphaMD For decades, men suffering from low testosterone faced an impossible choice: live with crushing fatigue, lost muscle, brain fog, and declining sexual function, or risk a cancer that could kill them

This review therefore examines how various synthesis methods and surface-engineering strategies influence the biomedical performance and associated applications of CQDs, while critically addressing the key challenges related to toxicity, standardisation, scalability, and clinical transition