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Wang B, Zhang J, Song F, Tian M, Shi B, Jiang H, et al

10.2337/db16-1088

In each coding exon of GHR, at least one molecular abnormality has been reported, but a poor genotypephenotype relationship has been demonstrated

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For instance, IL-4R signaling stimulates the M2 phenotype that determines liver inflammation and fibrosis in SSc (81, 117)