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Easy-to-administer nasal spray for convenient use
In severe acute pancreatitis (SAP), inflammatory factors promote the expression of matrix metalloproteinases (MMPs) and heparinases, which degrade syndecan-1 (SDC-1) and HS, while oxidative stress disrupts HA-CD44 binding, leading to increased capillary leakage and neutrophil adhesion
Neurochem J , 5 , 176182
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Subsequent post-hoc analysis revealed a significant difference between 24 h untreated and LPC-treated slices at 24 h (LPC: 54.10% 7.39%, p = 0.0001), 72 h (LPC: 58.24% 1.76%, p = 0.000002), 1 week (LPC: 50.5% 5.03%, p = 0.000002), 3 weeks (LPC: 67.95% 3.25%, p = 0.0001) and 5 weeks (LPC: 76.43% 6.83%, p = 0.024) post-treatment (Figure 5E)
For individuals with absorption difficulties, digestive conditions, or diagnosed deficiency, injections may be more appropriate than oral supplements
