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The study also revealed the underlying mechanism: autoantibodies and IFN- in SLE serum enhance the binding of the transcription suppressor CREM to the Gpx4 promoter, which in turn suppresses Gpx4 expression

1000 g daily) may be able to produce adequate absorption of vitamin B 12 even in the presence of intrinsic factor deficiency, and therefore may be an alternative to the intramuscular route for many people

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10.1016/j.brainres.2015.08.012 Brain Res

The design-rationale paper for the Phase 3 TRIUMPH basket trial obesity, OSA, knee OA, with a registrational endpoint structure that uses adiposity as a unifying disease-state framework

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