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These findings suggest that kokumi substances are divided into at least two groups: one that exerts its effect via interactions with kokumi receptors, and another that directly binds with T1Rs and other G-protein-coupled receptors and exerts its effect by allosteric modulation of these receptors

[DOI] [PubMed] [Google Scholar] 35.Malik Z, Ladan H, Nitzan Y

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For systemic inflammation, CRP findings were largely neutral in self-chosen diets