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Although the cognitive impairment of the EAAT3 knockout mice might be due also to impaired glutamate uptake, the authors concluded that NAC treatment reversed cognitive impairment, at least in part, by increasing neuronal GSH levels

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Similar content being viewed by others Overview of traumatic brain injury management and limited therapies In 2015, the United States Center for Disease Control (CDC) delivered its first report on traumatic brain injury (TBI) to the United States Congress, citing critical challenges related to injury detection and treatment [1]

Abstract Advanced ovarian cancer often presents with multiple lesions exhibiting varying responses to chemotherapy, highlighting the critical influence of the tumor microenvironment (TME)

Nevertheless, inactivation of GSTA4 remarkably increases cell susceptibility to chemotherapeutic agents in vitro and in the xenograft mouse model