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Over time, this buildup can contribute to neurological disorders, chronic fatigue, weakened immune function, and organ damage

10.1371/journal.pone.0038565 54 PrezS.Talns-ViscontiR.Rius-PrezS.FinamorI.SastreJ

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Remarkably, modifications neutralizing the charge on NACs carboxyl group, such as amidation or esterification, have been shown to significantly enhance its cellular uptake, as previously reported [25,26]

Microarray analyses and molecular profiling of steatosis induction in immortalized human hepatocytes