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doi: 10.1016/S1473-3099(08)70227-5 232 CritchleyJAYoungFOrtonLGarnerP

AMPK also modulates FA metabolism by reducing hydroxy methylglutaryl coenzyme A reductase (HCR) activity, a rate-limiting enzyme for cholesterol synthesis, via phosphorylation and degrading FOXO1 in ECs upon LS stimuli [218]