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Results Preclinical Assessment of Immunogenic Risk for AMG 966 In order to assess the immunogenic risk of AMG 966 and the charge pair mutations ( Supplementary Figure 1 ), an in silico analysis of MHC class II binding was performed using the Immune Epitope Database (IEDB) tool

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These reactions have as catalysts VIC-dependent dioxygenase enzymes such as prolyl 4-hydroxylase, prolyl 3-hydroxylase, and lysyl 5-hydroxylase [26,41,61]

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J Endo Metabol Res

Oxidative/Nitroxidative stress and multiple sclerosis