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After excluding irrelevant studies, we extracted key parameters (e.g., NCT number, phase, status, country, cell source, administration route, and main results) from eligible trials

Active DNA demethylation occurs under the catalysis by TET proteins, which sequentially oxidize 5-methylcytosine (5mC) to 5hmC, then to 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC) [38, 104, 126, 147]

Simultaneously, dopamine levels increased significantly from 29.17 6.39 ng/g in PD rats to 102.31 7.51 ng/g after treatment, though they remained below the control group level (135.90 9.21 ng/g)

D., Vinogradova E

2016 Sep 21 [Updated 2020 Jan 30]

This water is intended formultiple-dose use, with the bacteriostatic agent inhibiting the growth of bacteria, allowing the vial to be re-entered multiple times under aseptic conditions