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Clin Physiol Funct Imaging

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Current management combines lifestyle modifications (anti-inflammatory diet, exercise) with pharmacological therapies targeting specific disease manifestations to address the diverse clinical presentations of PCOS

2 Cross-species cell type comparisons and transcription factor code

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Leveraging AlphaFold, the structure of Fks1, the -1,3-glucan synthase targeted by echinocandins, was resolved, revealing resistance-associated mutations, catalytic mechanisms, and the GTP-dependent conformational activation by Rho1 (Hu et al., 2023