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Obesity and T2DM are both characterized by insulin resistance (IR), proinflammatory cytokines, mitochondrial dysfunction, endoplasmic reticulum stress as well as dysfunctional fatty acid metabolism [22]

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An array of preclinical and clinical studies have demonstrated that CBD possesses a variety of beneficial properties, including antioxidant, immunomodulatory, anti-inflammatory, neuroprotective, antipsychotic, procognitive, anti-anxiety, and anti-proliferative effects (Castillo et al

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