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A cortisone shot is a steroid injection often placed directly into or near a painful joint, bursa, tendon sheath, or inflamed area

While the accessibility may seem convenient, it introduces a range of risks that most people do not fully consider before they start

Cardiovascular Thrombotic Events Advise patients to be alert for the symptoms of cardiovascular thrombotic events, including chest pain, shortness of breath, weakness, or slurring of speech, and to report any of these symptoms to their health care provider immediately [see WARNINGS]

Table 2 summarizes these important protective mechanisms, including GPx4, -3 polyunsaturated fatty acids, and LPCAT3, which mitigate the negative effects of lipid peroxidation through different pathways

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doi: 10.1021/bi026681n