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During the initial trimester of pregnancy, fetal mitochondria exhibit a degree of immaturity and reduced expression of OCTs, suggesting that the administration of metformin in the first trimester is associated with a relatively low-risk profile

J Exp Bot 49:649667 Meister A, Anderson ME (1983) Glutathione

& Cohen, S

Nasal residence time and rheological properties of a new bentonite-based thixotropic gel emulsion nasal spray AM-301

Glutathione not only functions as the substrate for protein S-glutathionylation but can also reverse the process by reducing the cysteine in proteins to which glutathione is disulfide bonded forming oxidized glutathione, GSSG

Signal Transduct Target Ther 9:319