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Lukes Family Medicine Residency Program in Bethlehem, PA, provide a good overview of B12 deficiency recovery and the expected time it usually takes: Table 4 lists the usual times until improvement for abnormalities associated with vitamin B12 deficiency

Longer ester tail = slower release, longer half-life

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[74] Fruit and iron were also part of the diet, and it appears that at this point, Minot and Murphy were not quite sure that the liver was a very important factor