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What DBS does well Reduces off time and motor fluctuations Reduces levodopa-induced dyskinesias (often via the medication reduction permitted by improved control) Reduces tremor and rigidity, particularly with STN stimulation Approved and available in dozens of countries, including the US, UK, EU, Japan, Australia, and most APAC markets What DBS does not do Does not regenerate dopamine neurons Does not slow the underlying neurodegeneration Limited effect on axial symptoms such as gait freezing, postural instability, speech, and cognitive symptoms Carries surgical risks (haemorrhage, infection, device-related complications) and lifelong follow-up requirements Where DBS sits relative to Amchepry Both DBS and Amchepry involve stereotactic neurosurgery and general anaesthesia

Confocal microscope images were obtained from a confocal scanning microscope (LSM 880 with Airyscan, Carl zeiss, Germany)

Algarzae NK, Saleem U, Alsharif I, Alsulami T, Mostafa F, El-Nashar NM

La L-Glutathion est un antioxydant naturellement prsent dans le corps humain, y compris dans le foie, la rate et le cur

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