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Electrochemical studies showed that DNA binding of Endo III and MutY shifts the redox potentials of the 4Fe4S clusters, which sense DNA lesions via electron transfer (McGoldrick et al., 1995)

doi: 10.3390/biomedicines10071462

10.1016/j.atherosclerosis.2023.06.805 [DOI] [Google Scholar] 59

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Further research revealed that T - 5224 reduced the phosphorylation of components in the PI3K and AKT signaling pathways, suggesting that T - 5224 may induce ferroptosis in MM cells by regulating the PI3K/AKT signaling pathway (Tang S