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[DOI] [PubMed] [Google Scholar] 199.Huang S., Xu B., Liu Y

The cytoprotective (reduced reactive oxygen species and reduced cell senescence) effects of ergothioneine on endothelial cells exposed to hyperglycaemic conditions have been shown to be dependent on sirtuin 1 and sirtuin 6 activities and their cellular targets (Reference DOnofrio, Servillo and Giovane89) , which notably include NF- B, the aforementioned transcriptional regulator of SLC22A4 (Reference Maeda, Hirayama and Kobayashi63)

*Correspondence: Jingxin Mo, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Activated STAT5 forms homodimers, whereas active STAT1 and STAT3 form both homodimers and STAT1STAT3 heterodimers (Figure 3) (7, 102, 103)

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