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Drugs for bad bugs: confronting the challenges of antibacterial discovery

Effects of cooking The enzyme alliinase can be inactivated by heat

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Pharmacologic activation of this pathway by metformin amplifies Treg populations (90, 104), while glycolysis inhibition with 2-deoxyglucose (2-DG) shifts metabolism toward FAO, thereby promoting a phenotypic switch from Th17 to Treg cells (82)

Methods 16, 293310
