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JAMA 295 , 15391548 (2006)

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LXRs act as ligand-dependent transcription factors that form heterodimers with the retinoid X receptor (RXR), which then bind to LXR-responsive elements (LXREs) in DNA to promote the expression of target genes

Enhancing Tesofensine Results with Lifestyle Modifications While Tesofensine's potential to aid in weight management lies in its impact on neurotransmitters involved in appetite regulation, combining it with lifestyle interventions can significantly amplify its effectiveness

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