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This patient's young age, postpartum status, and diffusely enlarged thyroid without distinct palpable nodules make an activating mutation unlikely

doi: 10.1016/j.ecoenv.2021.112012 101 HaddadiAKessabiKBoughammouraSBen RhoumaMMloukaRBanniMet al

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Future therapies that are neuroprotective and disease-modifying, including novel delivery paradigms by which drugs could be targeted to the CNS to destroy the mutant Huntingtin protein and to arrest disease progression are urgently needed