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doi: 10.1677/JOE-10-0243

Both GSH deficiency and OxS were corrected only in OA receiving GlyNAC, and not in OA receiving isonitrogenous supplementation, which indicates that generalized protein supplementation does not improve intracellular GSH or OxS

Other therapeutic strategies for the treatment of human diseases In addition to nanomedical drug delivery systems, other modification technologies such as micromicellar systems and GalNAc modification are also used to improve the bioavailability of small molecule candidates targeting ferroptosis

Figure: Simplified ferroptotic cascade

GAPDH and -enolase also have decreased activity in AD brain, and were previously reported to be oxidatively modified [20

Cancer 101 , 278286 (2009)