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Ethics Approval and Informed Consent The study followed guidelines enshrined in the Declaration of Helsinki and was duly granted ethical clearance by Ethics Committee of Ruijin Hospital of Shanghai Jiao Tong University School of Medicine vide their approval number (2018) (145) , dated 29th August 2018

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We also showed that administration of vitamin C (200 mg/kg bw/day) improves antioxidant enzymes activity and decreases lipid peroxidation in these tissues and prevents oxidative stress (Figures 3-6) [5, 27, 38-40]

S., de Angelis, T

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