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In this regard, PDE4 inhibitors have suppressed cytokine production by T cells, as well as biomarkers of type 2 inflammation such as periostin and serpinB2 in asthma

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Author contributions ZH: Conceptualization, Methodology, Software, Validation, Visualization, Writing original draft, Writing review and editing

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The starting material N -Boc-4-aminophenol ( 4 ) was oxidized to corresponding N -Boc- p -benzoquinone imine ( 5 )

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doi: 10.1016/j.neubiorev.2019.01.003

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