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doi: 10.3389/fpls.2022.961864 29 LuoW

Autophagy in vivo More recent studies by In vitro studies by these investigators revealed that direct ethanol (100 mM) or acetaldehyde (100 or 500 M) exposure to ethanol-metabolizing VA-13 ADH+/CY P2E1 cells, suppressed intracellular autophagy, while exposure to each compound caused increased cellular expression of interleukin-6 (IL-6), a pro-inflammatory marker (Osna et al., 2017)

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Loss of PTEN Promotes Resistance to T-Cell-Mediated Immunotherapy

In Figure 3, we depicted the mechanisms of action of HIF-1 natural inhibitors, blocking different steps of the HIF-1 signaling pathway