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In fact, low to moderate levels play recognised physiological roles, including: Supporting immune cell signalling Participating in cell communication pathways Assisting in the regulation of vascular tone Common free radicals studied in oxidative stress research include: Problems arise only when free radical production exceeds the bodys neutralising capacity

Statements Data availability statement The bulk RNA-seq data have been uploaded to the Gene Expression Omnibus database (GSE327373)

& Hjorthj, C

10.1074/jbc.M602799200

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