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These studies suggest that the TMAO pathway driven by intestinal flora is closely related to microbial and host sterol and bile acid metabolism
Drug Discovery and Development of Novel Therapeutics for Inhibiting TMAO in Models of Atherosclerosis and Diabetes
McGlory, C., Calder, P
Furthermore, the molecular mechanisms of TMAO-induced endothelial dysfunction in experimental and clinical studies, as well as potential treatment strategies to prevent the progression of diseases triggered by TMAO, are also summarized
