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Statistical Analysis Statistical analysis was performed by parametric one-way analysis of variance (ANOVA), with the post hoc NewmanKeuls test, or non-parametric KruskalWallis test, followed by the Mann-Whitney U test to compare groups
Substrate specificity of TGM As KCs terminally differentiate into corneocytes, an early step in the formation of the cornified envelope is an attachment of involucrin to the inner surface of the cell membrane in a reaction catalyzed by the essential enzyme, TGM1 (Candi et al., 2005
