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These compounds include polyphenols, flavonoids, carotenoids, alkaloids, and terpenoids (Figure 1)

Furthermore, when millimolar quantities of ascorbate are oxidized to produce extracellular H 2 O 2 , as previously stated, large quantities of exogenous DHA are produced, as DHA is the primary oxidized form of Vit-C

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MH, AB, AJM received funding from BERG for the project

Doxycycline, another MMP inhibitor, effectively prevented collagen destruction induced by TB infection [46]

The inclusion of patients on diverse regimens, both preserved and preservative-free, supports the generalizability of the effects of the formulation across a representative spectrum of real-world therapy