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Preclinical studies have shown a favorable safety profile, but more rigorous clinical trials are necessary to fully understand its potential side effects and risks

It helps maintain the structural integrity of cartilage and may slow down cartilage breakdown

[DOI] [PMC free article] [PubMed] [Google Scholar] 186.Zhong J., Basu R., Guo D., Chow F.L., Byrns S., Schuster M., Loibner H., Wang X., Penninger J.M., Kassiri Z., et al

Though the results are controversial, as iron nanoparticles have no effect on the microbiota, zinc (Zn)-nanoparticles can have some beneficial effects, and other components such as silicon dioxide (SiO 2 ) nanoparticles may cause IEB disruption

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also known as PTP1D, SYP, SH-PTP2, and SH-PTP3) has ubiquitous expression