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First, obesity-related GH resistance in the liver, such as that characteristic of fatty liver, reduces IGF-1 production, leading to decreased serum IGF-1 levels 15

[DOI] [PubMed] [Google Scholar] 62.Goodman AL, McNulty NP, Zhao Y, Leip D, Mitra RD, Lozupone CA, Knight R, Gordon JI, Identifying genetic determinants needed to establish a human gut symbiont in its habitat

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