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In vitro , by decreasing the expression and nuclear localization of p-AKTSer473, Ferulin C (20M) significantly inhibited the expression and phosphorylation of AKT and its downstream member mTOR, thus inducing autophagy of tumor cells

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SL: Conceptualization, Writing review & editing, Project administration

110 A originates from the processing of the APP, a transmembrane glycoprotein, through its sequential cleavage by -secretase and -secretase (a multiprotein complex with PS1 or PS2 as catalytic subunits)