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Moreover, auto-antibodies in gastric juices bind and block the vitamin B 12 binding site of intrinsic factor and prevents the uptake of vitamin B 12

doi: 10.1155/2021/5529741 166 MehdizadehkashiARokhgirehSTahermaneshKEslahiNMinaeianSSamimiM

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Unlike most peptides, it is stable in gastric juice, which is part of why it is one of the most heavily researched peptides available