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Treatment with alprazolam was statistically significantly superior to placebo treatment, as measured by the following psychometric instruments: Hamilton Anxiety Rating Scale, Physicians Global Impressions, Target Symptoms, Patients Global Impressions and Self-Rating Symptom Scale

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[DOI] [PubMed] [Google Scholar] 199.Piletz J.E., Aricioglu F., Cheng J.T., Fairbanks C.A., Gilad V.H., Haenisch B., Halaris A., Hong S., Lee J.E., Li J., et al

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Int J Cell Biol 2013:180906

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The FGF21 produced by the liver enters the blood where is can then enter the brain and exert effects via binding to its receptor complex

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