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doi: 10.1186/s12868-015-0149-3

EGCG is a polyphenol that reduces SOD1 and TDP-43 aggregation in ALS pathology, while enhancing protein degradation pathways

The potential hepatotoxicity of herbal products has also been recognized in recent years (Stickel and Shouval, 2015)

Transferrin-bound iron (Fe 3+ ) is incorporated into the cell by binding to transferrin receptor 1 (TfR1) followed by subsequent endocytosis [9] and reduction to Fe 2+ by six-transmembrane epithelial antigen of prostate 3 (STEAP3) [10] (Fig

DiNicolantonio JJ, Beavers CJ, Menezes AR, Lavie CJ, OKeefe JH, Meier P, et al

Aspartate production by this route might under adverse conditions supplement the aspartate needed for transamination, when -ketoglutarate is converted to glutamate (Figures 3A,B)