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doi: 10.1126/scitranslmed.3001845

54 These species-specific patterns reflect underlying physiological characteristics, including the cell envelope, efflux systems, and thiol metabolism

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Furthermore, a crosstalk between insulin-induced ERK and epidermal growth factor (EGF) favored tumorigenesis by triggering the expression of anti-tumor immunity inhibitor programmed death-ligand 1 (PD-L1) in a cancer common in individuals with insulin resistance, pancreatic ductal adenocarcinoma (78)