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While each system detoxifies specific peroxides via GPx or Prx, they share substrates and can compensate for one another when impaired

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10.1136/gut.2009.202515 145 GeorgescuD.AncusaO.GeorgescuL.IonitaI.ReiszD

72 Ionizing radiation (IR), particularly at high doses (5 Gy), leads to irreversible DNA damage, triggering MSCs to form ectopically pigmented melanocytes (EPMs), which are associated with PHG